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Both genetic silencing of kindlin-2 and pirfenidone treatment have been shown to reduce PYCR1 activity, proline production, and fibrosis severity in vivo [14, 73]

Khavinson VK, Bondarev IE, Butyugov AA (2003) Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells

In melanoma, receptor-interacting protein 1 (RIP1) is often upregulated and promotes cancer cell proliferation by activating NF-B

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